In 2004, the frogs of El Copé, Panama, began dying by the thousands. The culprit: the deadly chytrid fungus Batrachochytrium dendrobatidis. Within months, roughly half of native frog species there went locally extinct. A new study suggests that frogs remaining in El Copé developed the ability to coexist with chytrid fungus due to ecological and/or evolutionary changes. The results could mean good news for other areas hit hard by chytrid fungus.